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Tetrasodium pyrophosphate

Chemical Name:
Tetrasodium pyrophosphate
pyro;TSPP;Nsc56751;victortspp;SODIUM DI;phosphotex;jiaolinsuanan;pyrophosphate;SODIUM DIPHOSPHATE;natriumpyrophosphat
Molecular Formula:
Formula Weight:
MOL File:
MSDS File:

Tetrasodium pyrophosphate Properties

Melting point
80 °C
Boiling point
93.8 °C
2.53 g/mL at 25 °C(lit.)
storage temp.
Inert atmosphere,Room Temperature
H2O: 0.1 M at 20 °C, clear, colorless
Specific Gravity
PH Range
Water Solubility
Soluble in water. Insoluble in ethyl alcohol.
Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference
7722-88-5(CAS DataBase Reference)
; ; ; ; ; ; ; ;
SCOGS (Select Committee on GRAS Substances)
Substances Added to Food (formerly EAFUS)
EWG's Food Scores
EPA Substance Registry System


Risk and Safety Statements

Signal word  Danger
Hazard statements  H315-H319-H335-H302-H318
Precautionary statements  P261-P280a-P304+P340-P405-P501a-P280-P305+P351+P338
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-41-22
Safety Statements  26-36-39
WGK Germany  3
RTECS  UX7350000
HS Code  28353990

Tetrasodium pyrophosphate price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S6422 Sodium pyrophosphate tetrabasic decahydrate BioXtra, 99.0-103.0% 7722-88-5 100 g $41.2 2021-12-16 Buy
Sigma-Aldrich P8010 Sodium pyrophosphate tetrabasic ≥95% 7722-88-5 500g $43.8 2021-12-16 Buy
Sigma-Aldrich 1.06591 tetra-Sodium diphosphate decahydrate for analysis EMSURE? ACS,Reag. Ph Eur 7722-88-5 500 g $90.09 2021-12-16 Buy
Sigma-Aldrich 71515 Sodium pyrophosphate tetrabasic decahydrate BioUltra, ≥99.5% (T) 7722-88-5 250 g $109 2021-12-16 Buy
Sigma-Aldrich S6422 Sodium pyrophosphate tetrabasic decahydrate BioXtra, 99.0-103.0% 7722-88-5 500 g $146 2021-12-16 Buy
Product number Packaging Price Buy
S6422 100 g $41.2 Buy
P8010 500g $43.8 Buy
1.06591 500 g $90.09 Buy
71515 250 g $109 Buy
S6422 500 g $146 Buy

Tetrasodium pyrophosphate Chemical Properties,Uses,Production


Sodium pyrophosphate, also called Tetrasodium pyrophosphate or TSPP is used in the laboratory as a buffering agent. The compound has been shown to be useful in the preparation of an EDTA-sodium pyrophosphate extraction buffer for microcystin analysis of soil samples. Tetrasodium pyrophosphate is an odorless, white powder or granules. It is used in water softener, buffering agent, thickening agent, dispersing agent, wool de-fatting agent, metal cleaner, soap and synthetic detergent builder, general sequestering agent, in electrodeposition of metals. It also acts as a tartar control agent in toothpaste and dental floss. In addition, it is used as a chelating agent in antimicrobial studies. It is also used as a food additive in common foods such as chicken nuggets, crab meat and canned tuna.

Chemical Properties

Tetrasodium pyrophosphate is a white crystalline powder or colourless crystals with the formula Na4P2O7. It contains the pyrophosphate ion and sodium cation. Toxicity is approximately twice that of table salt when ingested orally. There is also a hydrated form, Na4P2O7.10H2O.
Tetrasodium pyrophosphate
Tetrasodium pyrophosphate is used as a buffering agent, an emulsifier, a dispersing agent, and a thickening agent, and is often used as a food additive. It is widely used as an emulsifying salt (ES) in process cheese. Common foods containing sodium pyrophosphate include chicken nuggets, marshmallows, pudding, crab meat, imitation crab, canned tuna, and soy-based meat alternatives and cat foods and cat treats where it is used as a palatability enhancer. It is the active ingredient in Bakewell, the substitute for baking powder's acid component marketed during shortages in World War II. It is also used in some common baking powders.


Tetrasodium Pyrophosphate is a coagulant, emulsifier, and sequestrant that is mildly alkaline, with a ph of 10. it is moderately soluble in water, with a solubility of 0.8 g/100 ml at 25°c. it is used as a coagulant in noncooked instant puddings to provide thicken- ing. it functions in cheese to reduce the meltability and fat separa- tion. it is used as a dispersant in malted milk and chocolate drink powders. it prevents crystal formation in tuna. it is also termed sodium pyrophosphate, tetrasodium diphosphate, and tspp.


Pharmaceutic aid.
Tetrasodium pyrophosphate (Na4P2O7) is a non-toxic and biocompatible compound used as an electroactive media for exfoliation of the surface coating. It is also be used as an additive in the food industry.
Na4P2O7 can be used as an inorganic additive to improve the stability and electrochemical performance of redox flow batteries.


As a water softener; as a metal cleaner; as a dispersing and emulsifying agent.


Tetrasodium pyrophosphate is formed when pure disodium hydrogen orthophosphate is heated to 500℃ for 5 hours. The product will contain better than 98 per cent Na4P2O7. Crystalline masses large enough for optical measurements are produced by heating in platinum to above the melting point of the tetrasodium pyrophosphate, 800°, and cooling slowly. Higher temperatures or longer heating times do not change the tetrasodium pyrophosphate, as this is the final product in the dehydration of disodium hydrogen orthophosphate.

General Description

Odorless, white powder or granules. Mp: 995°C. Density: 2.53 g cm-3. Solubility in water: 3.16 g / 100 mL (cold water); 40.26 g / 100 mL boiling water. Used as a wool de-fatting agent, in bleaching operations, as a food additive. The related substance Tetrasodium pyrophosphate decahydrate (Na4P2O7 0H2O) occurs as colorless transparent crystals. Loses its water when heated to 93.8°C.

Reactivity Profile

Tetrasodium pyrophosphate is basic. Reacts exothermically with acids. Incompatible with strong oxidizing agents. Decomposes in ethyl alcohol.


Toxic by inhalation.

Health Hazard

Tetrasodium pyrophosphate (TSPP) is of low toxicity, but the dust may be irritating to the eyes, upper respiratory tract, and skin. Mild to moderate skin and eye irritation have occurred with acute exposure to the dust.

Safety Profile

Poison by ingestion, intraperitoneal, intravenous, and subcutaneous routes. It is not a cholinesterase inhibitor. When heated to decomposition it emits toxic fumes of POx and Na2O.

Tetrasodium pyrophosphate Preparation Products And Raw materials

Global( 376)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Dongdu Import and Export Co. LTD
+8615831048222 manager@cndongdu.com CHINA 589 58
+8618652417778 sales3257@jskolod.com China 129 60
0371-55170693 info@tianfuchem.com China 22039 55
0551-65418679 info@tnjchem.com China 2995 55
+86-0371-55982848 sales@coreychem.com China 29960 58
86-18871470254 linda@hubeijusheng.com CHINA 28229 58
Hebei Guanlang Biotechnology Co., Ltd.
+86-19930503282 +86-19930503282 alice@crovellbio.com China 5939 58
hdzhl biotechnology co., ltd
86-13032617415 sales@luchibiology.com CHINA 1275 58
+8613650506873 sales@chemdad.com CHINA 37442 58
Shaanxi Dideu Medichem Co. Ltd
+86-29-87569265 18612256290 Service@dideu.com China 3993 58

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View Lastest Price from Tetrasodium pyrophosphate manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2022-02-21 Tetrasodium Pyrophosphate
US $0.80 / KG 1T 96.5% 30 tons Hebei Dongdu Import and Export Co. LTD
2021-12-01 Tetrasodium pyrophosphate
US $2.60 / KG 1KG 99.5% 5000kg Hebei Crovell Biotech Co Ltd
2021-11-15 sodium pyrophosphate
US $2.00 / KG 2000KG 99% 500ton/Month Qiuxian Baitai New Material Co., LTD
pyrophosphatedesodium   jiaolinsuanan pyrophosphatetetrasodique  Sodiumpyrophosphate,anhydrous  sodiumpyrophosphate[na4p2o7]   tetranatriumpyrophosphat  tetrasodiumpyrophosphate,anhydrous  victortspp   Tetrasodium phosphonato phosphate Diphosphoric acid tetrasodium Sodium Pyrophosphate(Anhidride) SODIUM DI Nsc56751 Pyrophosphate sodium salt SodiuM Pyrophosphate Anhydrous FCC SODIUM PYROPHOSPHAYE Sodium pyrophosphate tetrabasic Vetec(TM) reagent grade, 95% SodiuM pyrophosphate tetrabasic >=95% Food Grade Sodium Pyrophosphate Anhydrous DIPHOSPHORIC ACID TETRASODIUM SALT DIPHOSPHORIC ACID, TETRASODIUM SALT, DECAHYDRATE DECAHYDRATE TETRASODIUM PYROPHOSPHATE TETRA-SODIUM DIPHOSPHATE TETRA-SODIUM DIPHOSPHATE-10-HYDRATE TETRA-SODIUM DIPHOSPHATE DECAHYDRATE TETRASODIUM PYROPHOSPHATE SODIUM DIPHOSPHATE SODIUM DIPHOSPHATE DECAHYDRATE SODIUM DIPHOSPHATE TETRABASIC DECAHYDRATE SODIUM PYROPHOSPHATE Sodium phosphate (pyro) PYROPHOSPHATE TETRASODIUM Sodium pyrophosphate tetrabasic anhydrous TetraSodiumPyrophosphateFoodGradeAnhydrous TetraSodiumPyrophosphateTechGradeAnhydrous Tetra-SodiumPyrophosphate(Anhydrous)E.P. sodium diphosphate tetrabasic sodium pyrophosphate tetrabasic sodium pyrophosphate, anhydrous, tech. SODIUMPYROPHOSPHATE,ANHYDROUS,POWDER,FCC phosphonooxyphosphonic acid Sodium Pyrophosphate Tetra, 10-Hydrate Sodium diphosphate tetrabasic, Tetrasodium pyrophosphate sodium pyophosphate,anhydrous for food anhydroustetrasodiumpyrophosphate   natriumpyrophosphat   phosphotex  pyro pyrophosphate   SODIUM PYROPHOSPHATE, 10-HYDRATE SODIUM PYROPHOSPHATE TETRABASIC DECAHYDRATE SODIUM TETRAPYROPHOSPHATE PYROPHOSPHATE INORGANIC Pyrophosphoric acid,tetrasodiumsalt TSPP Diphosphoric acid, sodium salt (1:4) Sodium pyrophosphate, 99%, for synthesis Tetrasodium pyrophosphate ISO 9001:2015 REACH