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Sodium pyruvate

CAS No.
113-24-6
Chemical Name:
Sodium pyruvate
Synonyms
PYR NA;PYRUVATE;p.A.,100g;binrongsuanna;SodiuM pyruvat;Sodium pyruate;SODIUM PYRUVATE;BioChemica,100g;SodiumPyruvate>SodiuM Pyruvate IH
CBNumber:
CB4252757
Molecular Formula:
C3H3NaO3
Formula Weight:
110.04
MOL File:
113-24-6.mol
MSDS File:
SDS

Sodium pyruvate Properties

Melting point
>300 °C (lit.)
Boiling point
>300℃
Density
1,267g/cm
refractive index
1,426-1,43
storage temp.
2-8°C
solubility
H2O: 100 mg/mL
form
solution
color
White to Pale Yellow
PH
pH(100g/l, 25℃) : 4.0～8.0
Water Solubility
Soluble in water.
BRN
3568341
Stability
Stable. Incompatible with strong oxidizing agents.
InChIKey
DAEPDZWVDSPTHF-UHFFFAOYSA-M
CAS DataBase Reference
113-24-6(CAS DataBase Reference)
EWG's Food Scores
FDA UNII
EPA Substance Registry System

SAFETY

Risk and Safety Statements

Hazard Codes  Xi
Risk Statements  36/38-36/37/38
Safety Statements  37/39-26-24/25-36
WGK Germany  3
TSCA  Yes
HS Code  29183000

Sodium pyruvate price More Price(58)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 792500 Sodium pyruvate anhydrous, free-flowing, Redi-Dri , ReagentPlus , ≥99% 113-24-6 100g $140 2021-12-16 Buy
Sigma-Aldrich 792500 Sodium pyruvate anhydrous, free-flowing, Redi-Dri , ReagentPlus , ≥99% 113-24-6 1kg $911 2021-12-16 Buy
TCI Chemical P0582 Sodium Pyruvate >97.0%(T) 113-24-6 25g $29 2022-04-27 Buy
TCI Chemical P0582 Sodium Pyruvate >97.0%(T) 113-24-6 500g $260 2022-04-27 Buy
Alfa Aesar A11148 Sodium pyruvate, 99% 113-24-6 250g $218 2021-12-16 Buy
Product number Packaging Price Buy
792500 100g $140 Buy
792500 1kg $911 Buy
P0582 25g $29 Buy
P0582 500g $260 Buy
A11148 250g $218 Buy

Sodium pyruvate Chemical Properties,Uses,Production

Description

Sodium pyruvate is the sodium salt of pyruvate. It is frequently supplemented to the cell culture medium to act as a source of energy since it is a key intermediate during the production of the high-energy ATP molecules inside cells. For example, it can be used as a carbon source for bacteria. It may also protect cell against hydrogen peroxide, an oxidant to scavenger oxygen radicals. It is an important metabolic intermediate in many essential metabolic pathways such as carbohydrate metabolism. For example, it is converted into acetyl coenzyme A and enters into the TCA cycle (Kreb’s cycle) in organisms. It is also involved in the amino acid metabolism in organisms.

Chemical Properties

White to slightly yellow crystalline pow

Uses

Intermediate in sugar metabolism and in enzymatic carbohydrate degradation (alcoholic fermentation) where it is converted to acetaldehyde and CO2 by carboxylase. In muscle, Pyruvic acid (derived from glycogen) is reduced to lactic acid during exertion, which is reoxidized and partially retransformed to glycogen during rest. The liver can convert Pyruvic acid to alanine by amination. A diagnostic agent for Parkinson disease

Uses

Sodium pyruvate is used in cell culture media as an additional source of energy. It acts as an antioxidant and finds protective effects against oxygen radicals. It serves as an intermediate in many metabolic pathways such as sugar metabolism. It is converted into acetyl coenzyme A and enters the trichloroacetic acid cycle. In addition, it is involved with amino acid metabolism and initiates the Kreb's cycle. It plays an important role as a free radical scavenger.

Uses

Sodium pyruvate has been used:
  • To prepare Bull Tyrode′s albumin-lactate-pyruvate diluent.
  • In pyruvate tolerance test.
  • To prepare oligodendrocyte culture medium.

Biological Functions

Sodium pyruvate (α-Ketopropionic acid sodium salt; 2-Oxopropanoic acid sodium salt；Pyruvic acid sodium; C3H3NaO3) as an important endogenous small molecules participates various tissue and organ metabolism processes that is the final product of glycolysis and the starting substrate for the tricarboxylic acid (TCA) cycle, and possesses antioxidant and scavenging free radical effects, thus widely using as buffer, excipient and antioxidant in medicine, diagnostic reagent and medical device.
Sodium pyruvate is an endogenous antioxidant and reactive oxygen radical scavenger. In this process, H2O2 or other reactive oxygen radicals are scavenged by sodium pyruvate by a nonenzymatic reaction or an oxidative dephosphorylation, and produce acetate, water and carbon dioxide. Thus, sodium pyruvate can suppress renal cellular injury induced by H2O2, such as lipid peroxidation of rat kidney homogenate, and cytosolic 51Cr release (a marker of cellular injury) from renal epithelial cells induced by H2O2. Thus, sodium pyruvate as effect antioxidant has potential in the clinical medication. Moreover, as effect antioxidant, sodium pyruvate is also as additives used in a vast range of foods and toiletries.

General Description

Sodium pyruvate (SP) is a simplest keto-acid. It crystallizes as very thin plates and belongs to the monoclinic system. Its utility in Knoevenagel condensation carried out in an aqueous medium has been examined. The standard molar enthalpy of formation and molar enthalpy of dissolution of SP at infinite dilution have been obtained. Its efficacy in treating mitochondrial DNA depletion syndromes has been investigated.

Biochem/physiol Actions

Sodium pyruvate is known to be an effective therapeutic target for type II citrullinaemia which is characterized by hyperammonaemia. In vivo studies proves that sodium pyruvate has protective function against hemorrhagic shock by preventing lipid peroxidation, NAD+ reduction and cleavage of poly(ADP-ribose) polymerases. Sodium pyruvate is also known to possess anti-inflammatory action and might show improvement in chronic lung disorder.

References

http://en.wikipedia.org/wiki/Sodium_pyruvate
Taidi, Behnam, et al. "Effect of carbon source and concentration on the molecular mass of poly (3-hydroxybutyrate) produced by Methylobacterium extorquens and Alcaligenes eutrophus." Applied microbiology and biotechnology 40.6 (1994): 786-790.
http://www.alfa.com/zh-cn/catalog/A11148/
http://bio.lonza.com/uploads/tx_mwaxmarketingmaterial/Lonza_BenchGuides_Sodium_Pyruvate_Solution_100mM.pdf

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View Lastest Price from Sodium pyruvate manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2022-03-25 sodium pyruvate
113-24-6
 US $0.00 / kg 1kg 99% 5tons Vertexyn (Nanjing) Bioworks Co., Ltd.
2022-03-04 Sodium pyruvate
113-24-6
 US $100.00 / bag 1bag 99 5000 Shanxi Naipu Import and Export Co.,Ltd
2022-02-24 Sodium pyruvate
113-24-6
 US $0.00 / Kg/Drum 1KG 99.9% 100000kg per month Wuhan Mulei New Material Technology Co. Ltd
  • sodium pyruvate
    113-24-6
  • US $0.00 / kg
  • 99%
  • Vertexyn (Nanjing) Bioworks Co., Ltd.
  • Sodium pyruvate
    113-24-6
  • US $100.00 / bag
  • 99
  • Shanxi Naipu Import and Export Co.,Ltd
  • Sodium pyruvate
    113-24-6
  • US $0.00 / Kg/Drum
  • 99.9%
  • Wuhan Mulei New Material Technology Co. Ltd
2-OXOPROPANOIC ACID SODIUM SALT 2-KETOPROPIONIC ACID SODIUM SALT Pyruvic acid, sodiuM salt, 99+% 100GR Pyruvic acid, sodiuM salt, 99+% 25GR SodiuM Pyruvate IH SODIUM PYRUVATE SODIUM ALPHA-KETOPROPIONATE sodium-2-ketopropionate SODIUM 2-OXOPROPANOATE SODIUM 2-OXOPROPIONATE PYRUVIC ACID NA-SALT PYRUVIC ACID SODIUM SALT PYRUVATE PYR NA ALPHA-KETOPROPIONIC ACID SODIUM SALT α-Ketopropionic acid sodium salt pyruvic acid hybri-max sodium pyruvic acid sodium SodiuM pyrovaceMate SodiuM α-ketopropionate Sodium pyruvate anhydrous, free-flowing, Redi-Dri(TM), ReagentPlus(R), >=99% Sodium pyruvate ReagentPlus(R), >=99% Sodium pyruvate Vetec(TM) reagent grade, 98% EDTA DISODIUM SALT DIHYDRATE BIOTECH GR SodiuM pyruvat POTASSIUM HYDROXIDE 0,1 MOL/L (ETOH) AVS Sodium Pyruvate Solution 100 mM (100X) Sodium Pyruvate, Animal-Free PYRUVIC ACID SODIUM CELL CULTURE TES SODIUM PYRUVATE BIOXTRA Sodium pyruvate,anhydrous, free-flowing Sodium-2-ketopropionate Sodium-2-oxopropanoate 2-oxo-propanoicacisodiumsalt  Propanoicacid,2-oxo-,sodiumsalt   binrongsuanna SODIUM PYRUVATE pure Sodium Pyruvate Solution 100 mM 2-Oxopropionic acid sodium salt α-Ketopropionic acid sodium salt, 2-Oxopropanoic acid sodium salt, Pyruvic acid sodium salt Sodium pyruvate,α-Ketopropionic acid sodium salt, 2-Oxopropanoic acid sodium salt, Pyruvic acid sodium salt PYRUVIC ACID SODIUM EMBRYO TESTED SODIUM PYRUVATE 100 MM SOLUTION*STERILE FILTERED CE PYRUVIC ACID SODIUM SIGMAULTRA SODIUM PYRUVATE, REAGENTPLUS TM, >= 99% PYRUVIC ACID SODIUM CELL CULTURE TESTED SodiumPyruvate,>99% SodiumPyruvateForBiochemistry RnaseA,PowderAndSolutionAvailable pyruvic acid sodium plant cell*culture tested Sodium pyruate sodium pyruvate 100 mm solution*sterile filtered p.A.,100g cellculturegrade,50g BioChemica,100g Sodium acetylformate Sodium pyroracemate Pyruvic acid, sodium salt, 99+% sodium pyruvate solution